Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.61 |
| ▸ | FNTA | P49354 | 3/20 | 0.59 |
| ▸ | FNTB | P49356 | 3/20 | 0.59 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331286 | 0.91 | MME (0.58) | MMEFNTAFNTBPGGT1B | |
| SCHEMBL9068699 | 0.91 | MME (0.53) | MMEFNTAFNTBPGGT1B | |
| SCHEMBL9621957 | 0.90 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL9621954 | 0.90 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL2867874 | 0.86 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL5966602 | 0.85 | GNPAT (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL1711691 | 0.85 | GNPAT (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL1711701 | 0.85 | GNPAT (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL29540393 | 0.85 | GNPAT (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL7292029 | 0.85 | GNPAT (0.52) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| US-4474799-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4474795-A | ANALGESICS, MERCAPTO-ALKANOYL AMINO ACIDS | E. R. SQUIBB & SONS, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4401677-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1983-08-30 | — | — | US | disclosed |