Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 3/20 | 0.50 |
| ▸ | FNTB | P49356 | 3/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319942 | 0.91 | MME (0.61) | MMEFNTAFNTBPGGT1B | |
| SCHEMBL29575686 | 0.87 | OPRD1 (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL9069637 | 0.86 | OPRK1 (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL29630731 | 0.85 | OPRD1 (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL29630760 | 0.85 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL29630522 | 0.84 | OPRD1 (0.49) | — | |
| SCHEMBL30692724 | 0.83 | OPRD1 (0.53) | — | |
| SCHEMBL7302272 | 0.83 | FOLH1 (0.50) | — | |
| SCHEMBL30264901 | 0.83 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL31122216 | 0.82 | OPRD1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |