Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313145 | 0.73 | PDE4A (0.43) | LMNATSHRMAPK1NPC1ALOX15 | |
| SCHEMBL7318644 | 0.71 | PDE3B (0.35) | LMNATSHRMAPK1NPC1ALOX15 | |
| SCHEMBL7320125 | 0.70 | PDE4A (0.43) | LMNATSHRMAPK1NPC1ALOX15 | |
| SCHEMBL7316957 | 0.69 | PDE3B (0.35) | LMNATSHRMAPK1NPC1ALOX15 | |
| SCHEMBL7317853 | 0.69 | KCNQ2 (0.39) | LMNATSHRMAPK1NPC1ALOX15 | |
| SCHEMBL7308383 | 0.68 | PDE3B (0.41) | LMNATSHRMAPK1NPC1ALOX15 | |
| SCHEMBL7312619 | 0.68 | PDE3B (0.33) | LMNANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7316967 | 0.67 | TSHR (0.37) | LMNATSHRMAPK1NPC1ALOX15 | |
| SCHEMBL7319375 | 0.64 | PDE3B (0.44) | — | |
| SCHEMBL7318255 | 0.64 | PDE4A (0.39) | S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |