Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316044 | 0.99 | RARB (0.59) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7319130 | 0.99 | RARB (0.59) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7340342 | 0.98 | NPC1 (0.59) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7332034 | 0.98 | NPC1 (0.59) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7320882 | 0.97 | MAPT (0.61) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7339155 | 0.93 | RAB9A (0.61) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7321777 | 0.90 | MAPT (0.64) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7324195 | 0.90 | MAPT (0.55) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7331263 | 0.89 | MAPT (0.56) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6914074 | 0.88 | RARB (0.70) | MAPTNPC1RAB9ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |