Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025469 | 0.87 | TLR7 (0.43) | AGTR1AGTR2TLR7 | |
| SCHEMBL6959483 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL765 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7319297 | 0.74 | TLR7 (0.48) | AGTR1AGTR2TLR7 | |
| SCHEMBL909 | 0.73 | AGTR1 (0.46) | AGTR1AGTR2TLR7 | |
| SCHEMBL910 | 0.73 | AGTR1 (0.46) | AGTR1AGTR2TLR7 | |
| SCHEMBL7315630 | 0.71 | AGTR1 (0.47) | AGTR1AGTR2TLR7 | |
| SCHEMBL18003756 | 0.71 | TLR7 (0.47) | AGTR1AGTR2TLR7 | |
| SCHEMBL8483902 | 0.69 | AGTR1 (0.44) | AGTR1AGTR2 | |
| Butane SCHEMBL10441839 | 0.69 | PPID (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995015325-A1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-08 | — | — | WO | disclosed |
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |