Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003756 | 0.86 | TLR7 (0.47) | TLR7AGTR1AGTR2 | |
| SCHEMBL7319297 | 0.85 | TLR7 (0.48) | TLR7AGTR1AGTR2 | |
| SCHEMBL649 | 0.84 | AGTR1 (0.58) | TLR7AGTR1AGTR2 | |
| SCHEMBL8483902 | 0.83 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9025469 | 0.82 | TLR7 (0.43) | TLR7LMNAKMT2AAGTR1AGTR2 | |
| SCHEMBL7321213 | 0.80 | AGTR1 (0.45) | TLR7AGTR1AGTR2 | |
| SCHEMBL161 | 0.79 | AGTR1 (0.53) | TLR7AGTR1AGTR2 | |
| SCHEMBL402 | 0.79 | AGTR1 (0.46) | TLR7ACHEAGTR1AGTR2 | |
| SCHEMBL7324827 | 0.78 | AGTR1 (0.54) | TLR7AGTR1AGTR2 | |
| SCHEMBL277 | 0.77 | AGTR1 (0.60) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |