Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320617 | 0.98 | REN (0.49) | REN | |
| SCHEMBL7309673 | 0.96 | REN (0.51) | REN | |
| SCHEMBL7311362 | 0.94 | REN (0.55) | REN | |
| SCHEMBL7316500 | 0.91 | REN (0.53) | REN | |
| SCHEMBL7310332 | 0.90 | REN (0.50) | REN | |
| SCHEMBL7313266 | 0.90 | REN (0.54) | REN | |
| SCHEMBL10602514 | 0.88 | REN (0.53) | REN | |
| SCHEMBL7316898 | 0.88 | REN (0.52) | REN | |
| SCHEMBL8896012 | 0.87 | REN (0.62) | REN | |
| SCHEMBL7318320 | 0.85 | REN (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114993-B1 | RENIN INHIBITORY TRIPEPTIDES | MERCK & CO. INC. (US) | 1990-05-16 | — | — | EP | claimed |
| US-4668770-A | HYPOTENSIVE, HYPOALDOSTERONISM | MERCK & CO., INC. (US) | 1987-05-26 | — | — | US | claimed |
| EP-0114993-A2 | Renin inhibitory tripeptides | MERCK & CO. INC. (US) | 1984-08-08 | — | — | EP | claimed |
| EP-0114993-B1 | RENIN INHIBITORY TRIPEPTIDES | MERCK & CO. INC. (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4668770-A | HYPOTENSIVE, HYPOALDOSTERONISM | MERCK & CO., INC. (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0114993-A2 | Renin inhibitory tripeptides | MERCK & CO. INC. (US) | 1984-08-08 | — | — | EP | disclosed |