Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315821 | 0.90 | THRA (0.35) | THRATHRBALDH1A1MAPTBCHE | |
| SCHEMBL7320201 | 0.85 | THRA (0.36) | THRATHRBBCHEACHEFFAR1 | |
| SCHEMBL10375783 | 0.80 | MAPT (0.41) | THRATHRBALDH1A1MAPTMEN1 | |
| SCHEMBL7310206 | 0.78 | MAPT (0.43) | ALDH1A1MAPTFFAR1FFAR4KDM4E | |
| SCHEMBL7319027 | 0.78 | FFAR4 (0.46) | FFAR1FFAR4HPGD | |
| SCHEMBL7313197 | 0.78 | THRA (0.36) | THRATHRBALDH1A1MAPTBCHE | |
| Hydrochloric Acid SCHEMBL7315798 | 0.77 | FFAR4 (0.46) | FFAR1FFAR4HPGD | |
| SCHEMBL7311177 | 0.76 | THRA (0.42) | THRATHRBALDH1A1MAPTVCAM1 | |
| SCHEMBL7315792 | 0.76 | FFAR4 (0.41) | ALDH1A1MAPTFFAR1FFAR4VCAM1 | |
| SCHEMBL7308504 | 0.76 | PDE3B (0.41) | ALDH1A1FFAR1FFAR4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |