Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320221 | 1.00 | PPARG (0.51) | PPARGPPARAPPARDFFAR1CYP4F2 | |
| SCHEMBL7320228 | 1.00 | PPARG (0.51) | PPARGPPARAPPARDFFAR1CYP4F2 | |
| SCHEMBL7296319 | 0.89 | PPARG (0.51) | PPARGPPARACYP4F2CYP4A11NFKB1 | |
| SCHEMBL7296313 | 0.89 | PPARG (0.51) | PPARGPPARACYP4F2CYP4A11NFKB1 | |
| SCHEMBL29586849 | 0.85 | CYP4F2 (0.53) | PPARGPPARAPPARDFFAR1CYP4F2 | |
| SCHEMBL7286847 | 0.85 | GLS (0.46) | PPARDFFAR1CA2CA5AMTNR1A | |
| SCHEMBL7286852 | 0.85 | GLS (0.46) | PPARDFFAR1CA2CA5AMTNR1A | |
| SCHEMBL431776 | 0.85 | PPARG (0.58) | PPARGPPARAPPARDFFAR1CYP4F2 | |
| SCHEMBL2133112 | 0.83 | PPARG (0.65) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL7313848 | 0.83 | CYP4F2 (0.60) | PPARGPPARAPPARDFFAR1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684039-A | Chroman-2-ylmethylamino derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5670667-A | DOPAMINE INHIBITORS FOR PSYCHOLOGICAL DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| US-5541199-A | DOPAMINE MODULATORS, SCHIZOPHRENIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |