Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7320336

CC(C)N1C(=O)CN(C(CC(=O)O)c2ccccc2)C(=O)c2cc(CCCCCN)ccc21.O=C(O)C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
RXRA P19793 2/20 0.35
SSTR1 P30872 9/20 0.35
SSTR4 P31391 9/20 0.35
SSTR5 P35346 9/20 0.35
SSTR2 P30874 8/20 0.35
SSTR3 P32745 7/20 0.35
ITGB3 P05106 4/20 0.34
ITGA2B P08514 4/20 0.34
S1PR4 O95977 1/20 0.33
S1PR1 P21453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7331380 0.90 MEN1 (0.43) MEN1KMT2ASSTR1SSTR4SSTR5
Trifluoroacetic Acid SCHEMBL7326440 0.89 ITGB3 (0.42) RXRASSTR1SSTR4SSTR5SSTR2
SCHEMBL7320340 0.89 MEN1 (0.35) MEN1KMT2ARXRASSTR1SSTR4
Trifluoroacetic Acid SCHEMBL7331607 0.89 MEN1 (0.38) MEN1KMT2ARXRAITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7326321 0.88 MEN1 (0.41) MEN1KMT2ASSTR1SSTR4SSTR5
Trifluoroacetic Acid SCHEMBL7332006 0.87 MEN1 (0.40) MEN1KMT2ASSTR1SSTR4SSTR5
Trifluoroacetic Acid SCHEMBL7319152 0.85 MEN1 (0.37) MEN1KMT2ARXRAITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7334590 0.83 MEN1 (0.36) MEN1KMT2ARXRAITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7329138 0.82 MDM2 (0.33) SSTR1SSTR4SSTR5SSTR2SSTR3
Trifluoroacetic Acid SCHEMBL7330695 0.81 ITGB3 (0.41) MEN1KMT2ASSTR1SSTR4SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5674863-A BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR GENENTECH, INC. (US) 1997-10-07 US disclosed
US-5674865-A BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR GENENTECH, INC. (US) 1997-10-07 US disclosed
US-5663166-A ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING GENENTECH, INC. (US) 1997-09-02 US disclosed
US-5565449-A PLATELET AGGREGATION INHIBITORS GENENTECH, INC. (US) 1996-10-15 US disclosed
EP-0610334-B1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR GENENTECH INC (US) 1996-01-24 EP disclosed
US-5403836-A Anticoagulants GENENTECH, INC. (US) 1995-04-04 US disclosed
EP-0610334-A1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. GENENTECH INC (US) 1994-08-17 EP disclosed
US-5250679-A Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor GENENTECH, INC. (US) 1993-10-05 US disclosed
WO-1993008174-A1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR GENENTECH, INC. (US) 1993-04-29 WO disclosed