Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 15/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310703 | 0.92 | PDE3B (0.40) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7310962 | 0.89 | PDE3B (0.43) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7312008 | 0.89 | SIRT5 (0.38) | PDE3BPDE3AP2RY12PDE2APLA2G4B | |
| SCHEMBL10375825 | 0.85 | PDE3B (0.45) | PDE3BPDE3ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7310371 | 0.84 | PDE3B (0.42) | PDE3BPDE3AP2RY12PDE2APPARG | |
| SCHEMBL10374532 | 0.82 | PDE3B (0.47) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7321124 | 0.82 | PDE3B (0.43) | PDE3BPDE3ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7307406 | 0.81 | PDE3B (0.39) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10377348 | 0.81 | PDE3B (0.52) | PDE3BPDE3ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10375674 | 0.80 | PDE3B (0.43) | PDE3BPDE3ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |