Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320586 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAALDH1A1L3MBTL1PPP1R15A | |
| SCHEMBL7322373 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1L3MBTL1PPP1R15A | |
| SCHEMBL7322381 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1L3MBTL1PPP1R15A | |
| SCHEMBL7984000 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1L3MBTL1PPP1R15A | |
| SCHEMBL7983994 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1L3MBTL1PPP1R15A | |
| SCHEMBL9760210 | 0.74 | MAPT (0.45) | SMN1; SMN2LMNAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL9760205 | 0.74 | MAPT (0.45) | SMN1; SMN2LMNAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL7281040 | 0.71 | KMT2A (0.39) | SMN1; SMN2LMNAALDH1A1L3MBTL1PPP1R15A | |
| SCHEMBL7281037 | 0.71 | KMT2A (0.39) | SMN1; SMN2LMNAALDH1A1L3MBTL1PPP1R15A | |
| SCHEMBL15026426 | 0.70 | CA1 (0.46) | SMN1; SMN2LMNAALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311053-A2 | Ameliorant of cerebral circulation and optical isomer of nb-818, processes for its production and its use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-12 | — | — | EP | claimed |
| US-5494923-A | Method of ameliorating cerebral circulation | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| US-5444077-A | Ameliorant of cerebral circulation and optical isomer of NB-818, processes for its use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0311053-A2 | Ameliorant of cerebral circulation and optical isomer of nb-818, processes for its production and its use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-12 | — | — | EP | disclosed |