Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.68 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.68 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411013 | 0.83 | HDAC3 (0.73) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL9157863 | 0.82 | ALDH1A1 (0.48) | HDAC6HDAC3NCOR2KDM4EALDH1A1 | |
| SCHEMBL22608571 | 0.81 | HDAC6 (1.00) | HDAC6HDAC3NCOR2LOXL2HDAC1 | |
| SCHEMBL2643238 | 0.79 | PLK1 (0.68) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL13009911 | 0.79 | HDAC6 (0.68) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL11131355 | 0.78 | HDAC3 (0.65) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL24892329 | 0.78 | PLAU (0.69) | HDAC6HDAC3NCOR2LOXL2KDM4E | |
| Hydrochloric Acid SCHEMBL17090887 | 0.78 | PLK1 (0.66) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL7119894 | 0.78 | HDAC6 (0.66) | HDAC6HDAC3NCOR2TPSAB1HDAC1 | |
| SCHEMBL23254636 | 0.76 | CYP1A2 (0.68) | HDAC6HDAC3NCOR2LOXL2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330925-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1989-09-06 | — | — | EP | disclosed |