Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7321060 | 0.99 | HDAC1 (0.57) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL7322814 | 0.93 | HDAC6 (0.56) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL7312341 | 0.92 | HDAC6 (0.55) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL5175761 | 0.91 | HDAC6 (0.69) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL7320637 | 0.90 | HDAC6 (0.68) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL7322365 | 0.86 | HDAC6 (0.54) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL7321234 | 0.85 | HDAC1 (0.46) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL7320956 | 0.83 | HDAC6 (0.64) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL18393994 | 0.83 | HDAC1 (0.53) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL7324476 | 0.82 | HDAC1 (0.53) | HDAC1HDAC6HDAC8HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034096-A | Compounds with anti-inflammatory and immunosuppressive activities | ITALFARMACO S.P.A. (IT) | 2000-03-07 | — | — | US | claimed |