Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.58 |
| ▸ | NPY1R | P25929 | 9/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.58 |
| ▸ | NPY2R | P49146 | 5/20 | 0.58 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23405249 | 0.89 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL23405252 | 0.89 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30678879 | 0.89 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL29959017 | 0.88 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL4728159 | 0.88 | NPY4R (0.69) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL4728153 | 0.88 | NPY4R (0.69) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31222396 | 0.88 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL7325656 | 0.88 | MME (0.54) | NPY4RNPY1RNPY5RNPY2RGNPAT | |
| SCHEMBL29959071 | 0.88 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30089310 | 0.88 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472380-A | CARBOXYALKYL DIPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4374829-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |