Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325243 | 0.87 | KIF11 (0.42) | KIF11SLC1A3SLC1A2SLC1A1SLC1A5 | |
| SCHEMBL7318340 | 0.85 | KIF11 (0.42) | KIF11SLC1A3SLC1A2SLC1A1SLC1A5 | |
| SCHEMBL7325902 | 0.83 | KIF11 (0.57) | KIF11SLC1A5 | |
| SCHEMBL7391083 | 0.70 | SLC1A3 (0.32) | KIF11SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7316648 | 0.68 | KIF11 (0.42) | KIF11SLC1A3SLC1A2SLC1A1SLC1A5 | |
| SCHEMBL7323114 | 0.68 | KIF11 (0.55) | KIF11SLC1A3SLC1A2SLC1A1SLC1A5 | |
| SCHEMBL7314907 | 0.68 | KIF11 (0.55) | KIF11SLC1A3SLC1A2SLC1A1SLC1A5 | |
| SCHEMBL7326141 | 0.68 | KIF11 (0.42) | KIF11SLC1A3SLC1A2SLC1A1SLC1A5 | |
| SCHEMBL7322800 | 0.67 | KIF11 (0.45) | KIF11SLC1A3SLC1A2SLC1A1SLC1A5 | |
| SCHEMBL7319059 | 0.66 | CHRM2 (0.42) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |