Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | RARB | P10826 | 4/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321811 | 0.99 | HDAC1 (0.66) | NR1H4HDAC1HDAC2HDAC6PKM | |
| SCHEMBL6538522 | 0.97 | NR1H4 (0.66) | NR1H4HDAC1HDAC2HDAC6PKM | |
| SCHEMBL5969241 | 0.89 | RARB (0.72) | NR1H4RARBPLA2G4BCSNK2A2CSNK2A1 | |
| SCHEMBL6539365 | 0.89 | NR1H4 (0.70) | NR1H4RARBPLA2G4BCSNK2A2CSNK2A1 | |
| SCHEMBL7316607 | 0.88 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6RARB | |
| SCHEMBL7341006 | 0.88 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6RARB | |
| SCHEMBL7332564 | 0.88 | RARB (0.75) | NR1H4RARBPLA2G4BCSNK2A2CSNK2A1 | |
| SCHEMBL7317106 | 0.88 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6RARB | |
| SCHEMBL6539567 | 0.88 | RARB (0.75) | NR1H4RARBPLA2G4BCSNK2A2CSNK2A1 | |
| SCHEMBL7316179 | 0.88 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |