Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322182 | 0.97 | NR1H4 (0.66) | NR1H4PKMHDAC1HDAC2HDAC6 | |
| SCHEMBL7321811 | 0.96 | HDAC1 (0.66) | NR1H4PKMHDAC1HDAC2HDAC6 | |
| SCHEMBL6539365 | 0.89 | NR1H4 (0.70) | NR1H4CSNK2A2CSNK2A1RARBPLA2G4B | |
| SCHEMBL6538456 | 0.87 | MAPT (0.66) | NR1H4HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL5969241 | 0.86 | RARB (0.72) | NR1H4CSNK2A2CSNK2A1RARBPLA2G4B | |
| SCHEMBL7316607 | 0.85 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6CSNK2A2 | |
| SCHEMBL7332564 | 0.85 | RARB (0.75) | NR1H4CSNK2A2CSNK2A1RARBPLA2G4B | |
| SCHEMBL7317106 | 0.85 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6CSNK2A2 | |
| SCHEMBL7316179 | 0.85 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6CSNK2A2 | |
| SCHEMBL7341006 | 0.85 | NR1H4 (0.65) | NR1H4HDAC1HDAC2HDAC6CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743776-B2 | ANTIFUNGAL, BETA-1,3-GLUCAN SYNTHASE INHIBITOR, PNEUMOCYSTIS CARINII; AMIDATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| US-20020193560-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-0941236-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998023637-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193560-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | NGLY1, CHIT1, MANBA | NR1H4 3597/4885PKM 1813/4885HDAC1 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.