Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | NAMPT | P43490 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125949 | 0.88 | HTT (0.67) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL8139902 | 0.87 | HTT (0.65) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL11988605 | 0.84 | SMN1; SMN2 (0.69) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL2940862 | 0.83 | SMN1; SMN2 (0.77) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL28120177 | 0.83 | SMN1; SMN2 (0.67) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL25232330 | 0.83 | SMN1; SMN2 (0.77) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL3905352 | 0.82 | HTT (0.59) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL22501702 | 0.81 | HTT (0.51) | HTTSMN1; SMN2MAPTNAMPTKMT2A | |
| SCHEMBL128190 | 0.81 | CA1 (0.70) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL5932688 | 0.81 | CYP1A2 (0.55) | HTTSMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |
| CN-1245486-A | Ketobenzamides as calpain inhibitors | BASF AG (DE) | 2000-02-23 | — | — | CN | disclosed |