SCHEMBL128190

SCHEMBL128190

CCOC(=O)c1ccc(CC)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.70
CA2 P00918 3/20 0.70
CA12 O43570 2/20 0.70
CA7 P43166 2/20 0.70
CA9 Q16790 2/20 0.70
CA14 Q9ULX7 2/20 0.70
ESR1 P03372 1/20 0.70
ESR2 Q92731 1/20 0.70
LMNA P02545 1/20 0.68
CYP1A2 P05177 1/20 0.68
CYP3A4 P08684 1/20 0.68
MAOA P21397 1/20 0.68
SMN1; SMN2 Q16637 2/20 0.64
HPGD P15428 4/20 0.59
HTT P42858 4/20 0.59
ALDH1A1 P00352 3/20 0.59
RECQL P46063 1/20 0.56
HSP90AA1 P07900 1/20 0.56
CACNA1B Q00975 1/20 0.56
APBA1 Q02410 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15672816 0.94 CA1 (0.63) CA1CA2CA12CA7CA9
SCHEMBL11291961 0.92 CA1 (0.61) CA1CA2CA12CA7CA9
SCHEMBL87450 0.91 CA1 (0.83) CA1CA2CA12CA7CA9
SCHEMBL21656957 0.91 CA12 (0.59) CA1CA2CA12CA7CA9
SCHEMBL12199135 0.89 CA1 (0.68) CA1CA2CA12CA7CA9
SCHEMBL29504635 0.89 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL21440358 0.89 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL7746905 0.89 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL30271267 0.89 CA1 (0.79) CA1CA2CA12CA7CA9
SCHEMBL27647500 0.89 CA1 (0.79) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909169-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN claimed
US-9620718-B2 Method for preparing a semiconducting layer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-04-11 US claimed
WO-2016022421-A1 SOLID CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION AND METHODS OF MAKING AND USING THE SAME BASF CORPORATION (US) 2016-02-11 WO claimed
CN-105287483-A Application of propionamide compounds TIANJIN INTERNAT JOINT ACADEMY OF BIOMEDICINE 2016-02-03 CN claimed
CN-105267191-A Application of propanamide compound TIANJIN INTERNAT JOINT ACADEMY OF BIOMEDICINE 2016-01-27 CN claimed
US-20150188053-A1 METHOD FOR PREPARING A SEMICONDUCTING LAYER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-07-02 US claimed
WO-2013190255-A9 METHOD FOR PREPARING A SEMICONDUCTING LAYER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-01-08 WO claimed
WO-2013190255-A2 METHOD FOR PREPARING A SEMICONDUCTING LAYER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-12-27 WO claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
US-6420398-B2 FOR TREATING AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS; 4-(3-(2-(ACETYLTHIO)ETHYL)-3-(2-CYCLOHEXYLETHYL)-UREIDOMETHYL)-1 -METHYLPYRIDINIUM IODIDE, FOR EXAMPLE; INHIBIT PRODUCTION OF TUMOR NECROSIS FACTOR ALPHA (TNF-A) SANTEN PHARMACEUTICAL CO., LTD. (JP) 2002-07-16 US claimed
US-20010041725-A1 Novel urea derivatives having nitrogen aromatic heterocycle SANTEN PHARMACEUTICAL CO., LTD. (JP) 2001-11-15 US claimed
EP-1103543-A1 NOVEL UREA DERIVATIVES BEARING NITROGENOUS AROMATIC HETEROCYCLES SANTEN PHARMACEUTICAL CO., LTD. (JP) 2001-05-30 EP claimed
CN-118909169-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-118909168-A Catalyst system for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-118909170-A Catalyst system for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-113845427-B Aryl alcohol, aryl ketone, aryl carboxylic acid compound, and synthetic method and application thereof 华东师范大学 2024-06-25 CN disclosed
US-4159965-A COORDINATION CATALYSTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-07-03 US disclosed
US-4159256-A MAGNESIUM, TITANIUM, SILICON CATALYST ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-06-26 US disclosed
US-4143223-A TITANIUM, HALOGEN, ALUMINUM, ESTER AND AN ALCOHOL MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1979-03-06 US disclosed
US-4069169-A TITANIUM TETRAHALIDE, BENZOIC ACID ESTER DERIVATIVES MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010041725-A1 Novel urea derivatives having nitrogen aromatic heterocycle TNF, UACA, HRH4 CA1 3854/4885CA2 4105/4885CA12 4578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.