Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.83 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329974 | 1.00 | MME (0.83) | MMEPPARGPPARDKDM4EPPARA | |
| Candoxatril SCHEMBL1649937 | 0.91 | MME (1.00) | MMEPPARGPPARDKDM4EPPARA | |
| Candoxatril SCHEMBL5601069 | 0.91 | MME (1.00) | MMEPPARGPPARDKDM4EPPARA | |
| Candoxatril SCHEMBL29494166 | 0.91 | MME (1.00) | MMEPPARGPPARDKDM4EPPARA | |
| Candoxatril SCHEMBL121666 | 0.91 | MME (1.00) | MMEPPARGPPARDKDM4EPPARA | |
| Candoxatril SCHEMBL392920 | 0.91 | MME (1.00) | MMEPPARGPPARDKDM4EPPARA | |
| SCHEMBL16624679 | 0.91 | MME (0.85) | MMEPPARGPPARDKDM4EPPARA | |
| SCHEMBL9470376 | 0.89 | MME (0.88) | MMEPPARGPPARDKDM4EPPARA | |
| Candoxatril SCHEMBL14660450 | 0.89 | MME (0.95) | MMEPPARGPPARDKDM4EPPARA | |
| SCHEMBL9469895 | 0.85 | MME (0.80) | MMEPPARGPPARDKDM4EPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342850-B1 | ENANTIOMERIC GLUTARAMIDE DIURETIC AGENTS | Pfizer Limited (GB) | 1992-05-20 | — | — | EP | claimed |