Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407223 | 0.78 | KMT2A (0.35) | ALDH1A1KMT2AMAPK1MEN1MAPT | |
| SCHEMBL3404247 | 0.78 | DPP4 (0.43) | ALDH1A1KMT2AMAPK1MEN1MAPT | |
| SCHEMBL1983726 | 0.77 | CYP2C19 (0.41) | ALDH1A1KMT2AMAPK1MEN1HPGD | |
| SCHEMBL7310502 | 0.75 | CYP2C19 (0.42) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL11619698 | 0.75 | KMT2A (0.42) | ALDH1A1KMT2AMAPK1MEN1MAPT | |
| SCHEMBL27174624 | 0.72 | IDO1 (0.39) | ALDH1A1KMT2AMAPK1MEN1MAPT | |
| SCHEMBL11356323 | 0.70 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL29093049 | 0.70 | IDO1 (0.41) | ALDH1A1KMT2AMAPK1MEN1MAPT | |
| SCHEMBL23341293 | 0.68 | TP53 (0.39) | ALDH1A1TSHRCTSLCTSB | |
| SCHEMBL23341266 | 0.68 | IDO1 (0.39) | ALDH1A1TSHRCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273645-A2 | Novel derivatives of arginine vasopressin antagonists | THE MEDICAL COLLEGE OF OHIO (US) | 1988-07-06 | — | — | EP | disclosed |