SCHEMBL7323402

SCHEMBL7323402

CCC(C)CNC(=O)C(CC(O)C(CC1CCCCC1)NC(=O)C(Cc1cscn1)NC(=O)C(Cc1cccc2ccccc12)NC(=O)CN1CCOCC1)C(C)(C)O

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7327962 1.00 REN (0.53) REN
SCHEMBL7327958 1.00 REN (0.53) REN
SCHEMBL7323412 1.00 REN (0.53) REN
SCHEMBL7321566 0.90 REN (0.61) REN
SCHEMBL7321569 0.90 REN (0.61) REN
SCHEMBL7323085 0.90 REN (0.61) REN
SCHEMBL7323079 0.90 REN (0.61) REN
Morpholine SCHEMBL7435925 0.89 REN (0.53) REN
SCHEMBL10339038 0.89 REN (0.50) REN
SCHEMBL29557925 0.82 REN (0.54) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5364844-A Hypotensive agents SANKYO COMPANY, LIMITED (JP) 1994-11-15 — — US claimed
EP-0326364-B1 Renin inhibitory oligopeptides, their preparation and use SANKYO CO (JP) 1994-06-22 — — EP claimed
EP-0326364-A2 Renin inhibitory oligopeptides, their preparation and use Sankyo Company Limited (JP) 1989-08-02 — — EP claimed
US-5364844-A Hypotensive agents SANKYO COMPANY, LIMITED (JP) 1994-11-15 — — US disclosed
EP-0326364-A2 Renin inhibitory oligopeptides, their preparation and use Sankyo Company Limited (JP) 1989-08-02 — — EP disclosed
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