Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.44 |
| ▸ | NPY4R | P50391 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7333452 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BNPY4RRXRAITGA2 | |
| Trifluoroacetic Acid SCHEMBL7331607 | 0.90 | MEN1 (0.38) | ITGB3ITGA2BNPY4RRXRA | |
| SCHEMBL7323748 | 0.89 | ITGB3 (0.37) | ITGB3ITGA2BNPY4RRXRA | |
| Trifluoroacetic Acid SCHEMBL7333906 | 0.89 | ITGB3 (0.42) | ITGB3ITGA2BNPY4RITGA2 | |
| Trifluoroacetic Acid SCHEMBL7330476 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BNPY4R | |
| Trifluoroacetic Acid SCHEMBL7326440 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BRXRAITGA2S1PR4 | |
| SCHEMBL7331609 | 0.84 | ITGB3 (0.33) | ITGB3ITGA2BRXRA | |
| Trifluoroacetic Acid SCHEMBL7331099 | 0.81 | NPY4R (0.33) | ITGB3ITGA2BNPY4R | |
| Trifluoroacetic Acid SCHEMBL7334280 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BNPY4R | |
| SCHEMBL7333455 | 0.81 | ITGB3 (0.45) | ITGB3ITGA2BNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674863-A | BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR | GENENTECH, INC. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5674865-A | BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR | GENENTECH, INC. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5403836-A | Anticoagulants | GENENTECH, INC. (US) | 1995-04-04 | — | — | US | disclosed |
| US-5250679-A | Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor | GENENTECH, INC. (US) | 1993-10-05 | — | — | US | disclosed |
| WO-1993008174-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1993-04-29 | — | — | WO | disclosed |