Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 6/20 | 0.47 |
| ▸ | CTSB | P07858 | 5/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325903 | 0.94 | TYR (0.55) | TYRALDH1A1ALOX15CTSLCTSB | |
| SCHEMBL27406872 | 0.93 | TYR (0.55) | TYREGFRALDH1A1ALOX15CTSL | |
| SCHEMBL7296176 | 0.93 | TYR (0.55) | TYREGFRALDH1A1ALOX15CTSL | |
| SCHEMBL7437357 | 0.86 | TYR (0.62) | TYRALDH1A1ALOX15CTSLCTSB | |
| SCHEMBL5802843 | 0.86 | TYR (0.62) | TYRALDH1A1ALOX15CTSLCTSB | |
| SCHEMBL29559972 | 0.86 | TYR (0.62) | TYRALDH1A1ALOX15CTSLCTSB | |
| SCHEMBL12937731 | 0.84 | SIRT2 (0.48) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL3657799 | 0.84 | SIRT2 (0.48) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL12937725 | 0.84 | SIRT2 (0.48) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL2947377 | 0.84 | LCK (0.61) | TYRALDH1A1ALOX15CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352815-B1 | PRODRUGS OF DOPAMINE | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5013753-A | Prodrugs of dopamine | SIMES (IT) | 1991-05-07 | — | — | US | disclosed |