Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406872 | 1.00 | TYR (0.55) | TYREGFRCTSLCTSBCTSS | |
| SCHEMBL5802843 | 0.93 | TYR (0.62) | TYRCTSLCTSBCTSSCTSK | |
| SCHEMBL29559972 | 0.93 | TYR (0.62) | TYRCTSLCTSBCTSSCTSK | |
| SCHEMBL7437357 | 0.93 | TYR (0.62) | TYRCTSLCTSBCTSSCTSK | |
| SCHEMBL7323846 | 0.93 | TYR (0.49) | TYREGFRCTSLCTSBCTSS | |
| SCHEMBL2947377 | 0.91 | LCK (0.61) | TYRCTSLCTSBCTSSCTSK | |
| SCHEMBL9744805 | 0.88 | TYR (0.58) | TYRCTSLCTSBCTSSCTSK | |
| SCHEMBL9744810 | 0.88 | TYR (0.58) | TYRCTSLCTSBCTSSCTSK | |
| SCHEMBL30319896 | 0.88 | TYR (0.58) | TYRCTSLCTSBCTSSCTSK | |
| SCHEMBL11199738 | 0.88 | CTSL (0.62) | TYRCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393781-B1 | Dopamine pro-drug | ZAMBON SPA (IT) | 1995-02-08 | — | — | EP | disclosed |
| EP-0607394-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994003461-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |
| US-5073547-A | DOPAMINE PRO-DRUG | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-17 | — | — | US | disclosed |
| EP-0393781-A2 | Dopamine pro-drug | ZAMBON GROUP S.p.A. (IT) | 1990-10-24 | — | — | EP | disclosed |