Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.63 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317986 | 0.97 | RARB (0.68) | RARBPLK1MMP1TP53TSHR | |
| SCHEMBL7326374 | 0.95 | RARB (0.71) | RARBPLK1TP53TSHRPLA2G4B | |
| SCHEMBL7325242 | 0.95 | RARB (0.71) | RARBPLK1TP53TSHRPLA2G4B | |
| SCHEMBL10762321 | 0.95 | PLK1 (0.65) | PLK1MMP1LMNASMN1; SMN2GAA | |
| SCHEMBL6538458 | 0.94 | PLK1 (0.69) | RARBPLK1SMN1; SMN2CA1CA2 | |
| SCHEMBL7330555 | 0.92 | TP53 (0.66) | RARBPLK1MMP1CA1CA2 | |
| SCHEMBL28467816 | 0.90 | TP53 (0.69) | RARBTP53TSHRPLA2G4B | |
| SCHEMBL4822746 | 0.90 | TP53 (0.69) | RARBTP53TSHRPLA2G4B | |
| SCHEMBL9242371 | 0.90 | TP53 (0.69) | RARBTP53TSHRPLA2G4B | |
| SCHEMBL3952381 | 0.90 | TP53 (0.69) | RARBTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240713-C | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-02-08 | — | — | CN | disclosed |
| CN-1296494-A | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-05-23 | — | — | CN | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |