SCHEMBL7326374

SCHEMBL7326374

CCCCCCOc1ccc(-c2ccc(C(=O)NN)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.71
TP53 P04637 1/20 0.63
TSHR P16473 1/20 0.63
PLA2G4B P0C869 1/20 0.61
SPHK1 Q9NYA1 3/20 0.60
PPARG P37231 3/20 0.59
PPARA Q07869 1/20 0.59
PLK1 P53350 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7325242 1.00 RARB (0.71) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL7317986 0.98 RARB (0.68) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL27767036 0.95 TP53 (0.69) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL9242371 0.95 TP53 (0.69) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL7734803 0.95 TP53 (0.69) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL3952381 0.95 TP53 (0.69) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL9242353 0.95 TP53 (0.69) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL4822746 0.95 TP53 (0.69) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL28467816 0.95 TP53 (0.69) RARBTP53TSHRPLA2G4BSPHK1
SCHEMBL7323928 0.95 RARB (0.63) RARBTP53TSHRPLA2G4BPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232290-B1 FUNGICIDES AGAINST PNEUMOCYSTIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-15 US disclosed
EP-1053247-A1 ANTIFUNGAL CYCLOHEXAPEPTIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-11-22 EP disclosed
WO-1999040108-A1 NEW COMPOUND FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-08-12 WO disclosed