Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 10/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326045 | 0.93 | MDM2 (0.33) | MDM2 | |
| SCHEMBL7331753 | 0.92 | MDM2 (0.31) | MDM2 | |
| Trifluoroacetic Acid SCHEMBL7324076 | 0.92 | MDM2 (0.34) | MDM2XIAPTP53 | |
| SCHEMBL8842984 | 0.91 | — | — | |
| SCHEMBL7324426 | 0.91 | — | — | |
| SCHEMBL7330220 | 0.88 | MDM2 (0.35) | MDM2 | |
| SCHEMBL8842838 | 0.88 | — | — | |
| SCHEMBL7329669 | 0.86 | PTGDR2 (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL7326038 | 0.85 | MDM2 (0.34) | MDM2TP53 | |
| SCHEMBL7360313 | 0.85 | MDM2 (0.35) | MDM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993008174-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1993-04-29 | — | — | WO | disclosed |