Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29161535 | 0.85 | L3MBTL1 (0.61) | ABCB1L3MBTL1HPGDHSD17B10GLA | |
| SCHEMBL8381868 | 0.85 | L3MBTL1 (0.66) | ABCB1L3MBTL1HPGDHSD17B10GLA | |
| SCHEMBL30774303 | 0.85 | L3MBTL1 (0.66) | ABCB1L3MBTL1HPGDHSD17B10GLA | |
| SCHEMBL3641468 | 0.84 | L3MBTL1 (0.69) | ABCB1L3MBTL1HPGDHSD17B10GLA | |
| SCHEMBL1089156 | 0.84 | L3MBTL1 (0.69) | ABCB1L3MBTL1HPGDHSD17B10GLA | |
| SCHEMBL27484768 | 0.81 | CYP1A2 (0.67) | HPGDHSD17B10TSHRMEN1KMT2A | |
| SCHEMBL5320912 | 0.81 | HTR3B (0.69) | HPGDHSD17B10TSHRMEN1KMT2A | |
| SCHEMBL4095134 | 0.81 | KDM4E (0.69) | HPGDHSD17B10GLAGAATSHR | |
| SCHEMBL24951311 | 0.81 | HPGD (0.48) | ABCB1L3MBTL1HPGDHSD17B10GLA | |
| SCHEMBL4091176 | 0.80 | ABCB1 (0.78) | ABCB1L3MBTL1HSD17B10TSHRACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535104-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1996-09-04 | — | — | EP | disclosed |
| US-5371080-A | Central nervous system disorders | NOVO NORDISK A/S | 1994-12-06 | — | — | US | disclosed |
| US-5276028-A | Psychological disorders, anticonvulsants, anxiolytic or hypnotics and cognition activators | NORDISK A/S (DK) | 1994-01-04 | — | — | US | disclosed |
| EP-0535104-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000298-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-09 | — | — | WO | disclosed |