Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL635142 | 0.79 | NQO1 (0.61) | NQO1LTA4HTSHRTDP1PLK1 | |
| SCHEMBL6205456 | 0.78 | TP53 (0.49) | NQO1LTA4HTDP1MAPTKDM4E | |
| SCHEMBL18910985 | 0.78 | NQO1 (0.58) | NQO1LTA4HTSHRTDP1PLK1 | |
| SCHEMBL13211690 | 0.76 | NQO1 (0.70) | NQO1LTA4HTSHRTDP1PLK1 | |
| SCHEMBL11547049 | 0.75 | NQO1 (0.61) | NQO1LTA4HTSHRTDP1PLK1 | |
| 1,4-Diethoxybenzene SCHEMBL27616183 | 0.75 | NQO1 (0.88) | NQO1LTA4HTSHRTDP1PLK1 | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.75 | NQO1 (1.00) | NQO1LTA4HTSHRTDP1PLK1 | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.75 | NQO1 (1.00) | NQO1LTA4HTSHRTDP1PLK1 | |
| SCHEMBL13311537 | 0.74 | NQO1 (0.67) | NQO1LTA4HTSHRTDP1PLK1 | |
| SCHEMBL3035998 | 0.74 | NQO1 (0.67) | NQO1LTA4HTSHRTDP1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660715-A1 | CARBOSTYRIL DERIVATIVES AS ANTIARRHYTHMIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006427-A1 | CARBOSTYRIL DERIVATIVES AS ANTIARRHYTHMIC AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-03-31 | — | — | WO | disclosed |