Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336081 | 1.00 | MAPT (0.68) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL7325780 | 1.00 | MAPT (0.68) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL7322722 | 0.96 | MAPT (0.62) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL6132720 | 0.94 | MAPT (0.77) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL10295289 | 0.94 | MAPT (0.77) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL7324122 | 0.94 | MAPT (0.77) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL6132617 | 0.94 | MAPT (0.77) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL15693338 | 0.92 | MAPT (0.79) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL6539579 | 0.91 | MAPT (0.64) | MAPTRAB9ALMNAKMT2AHTT | |
| SCHEMBL7339228 | 0.91 | MAPT (0.64) | MAPTRAB9ALMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |