Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336081 | 0.96 | MAPT (0.68) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL7325780 | 0.96 | MAPT (0.68) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL7324912 | 0.96 | MAPT (0.68) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL14926518 | 0.94 | MAPT (0.70) | MAPTRAB9ARARBGAAL3MBTL1 | |
| SCHEMBL7321276 | 0.93 | MAPT (0.72) | MAPTRAB9ARARBKMT2AALDH1A1 | |
| SCHEMBL7317829 | 0.92 | RARB (0.64) | MAPTRAB9ARARBKMT2ALMNA | |
| SCHEMBL7325818 | 0.92 | RARB (0.64) | MAPTRAB9ARARBKMT2ALMNA | |
| SCHEMBL7316188 | 0.90 | RARB (0.62) | MAPTRAB9ARARBKMT2AGAA | |
| SCHEMBL7316966 | 0.90 | MAPT (0.71) | MAPTRAB9ARARBKMT2AALDH1A1 | |
| SCHEMBL7322270 | 0.90 | MAPT (0.64) | MAPTRAB9ARARBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |