Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074431 | 0.87 | MAPT (0.60) | MAPTHDAC8ALDH1A1TSHRHSD17B10 | |
| SCHEMBL2778 | 0.85 | TSHR (0.52) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 | |
| SCHEMBL30084385 | 0.85 | TSHR (0.52) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 | |
| SCHEMBL27931437 | 0.83 | TSHR (0.50) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 | |
| Acetone SCHEMBL29281281 | 0.83 | TSHR (0.50) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1896602 | 0.83 | TSHR (0.50) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 | |
| SCHEMBL28206063 | 0.83 | TSHR (0.50) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6383298 | 0.83 | TSHR (0.50) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9897059 | 0.82 | ITGB1 (0.38) | MAPTHDAC8ITGB1ITGA5ALDH1A1 | |
| Acetic Acid SCHEMBL28536661 | 0.81 | TSHR (0.48) | ITGB1ITGA5ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437886-A2 | Stabilizer composition for polymers of vinyl chloride and polymeric compositions containing such compositions | EUROPEAN VINYLS CORPORATION (ITALIA) S.p.A. (IT) | 1991-07-24 | — | — | EP | claimed |
| EP-0664806-A1 | HETEROCYCLIC CONDENSED BENZOIC ACID DERIVATIVES AS 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008995-A1 | HETEROCYCLIC CONDENSED BENZOIC ACID DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-28 | — | — | WO | disclosed |
| CN-1019667-B | Process for preparing benzothiazinone derivatives | SHELL INT RESEARCH (NL) | 1992-12-30 | — | — | CN | disclosed |
| EP-0437886-A2 | Stabilizer composition for polymers of vinyl chloride and polymeric compositions containing such compositions | EUROPEAN VINYLS CORPORATION (ITALIA) S.p.A. (IT) | 1991-07-24 | — | — | EP | disclosed |
| CN-87104156-A | Benzo buprofezin derivate | — | 1987-12-16 | — | — | CN | disclosed |