Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460736 | 0.91 | AGTR1 (0.62) | PPARGAGTR1AGTR2 | |
| SCHEMBL688 | 0.87 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL24943510 | 0.85 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL10533959 | 0.83 | PPARG (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL30153502 | 0.83 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL9402044 | 0.83 | PPARG (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL9198402 | 0.83 | PPARG (0.61) | PPARG | |
| SCHEMBL3459616 | 0.82 | PPARG (0.59) | PPARGAGTR1AGTR2 | |
| SCHEMBL13368447 | 0.82 | PPARG (0.60) | PPARGAGTR1AGTR2 | |
| SCHEMBL12716740 | 0.82 | PPARG (0.61) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |