Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.69 |
| ▸ | HTR2A | P28223 | 5/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333643 | 0.86 | DRD2 (0.75) | DRD2HTR2AKDM4EMAPTALOX15 | |
| SCHEMBL7332229 | 0.85 | DRD2 (0.77) | DRD2HTR2AHRH3KDM4EMAPT | |
| SCHEMBL7328205 | 0.84 | DRD2 (0.75) | DRD2HTR2AKDM4EMAPTALOX15 | |
| SCHEMBL7324018 | 0.82 | HTR2A (0.70) | DRD2HTR2AKDM4EMAPTALOX15 | |
| SCHEMBL7330537 | 0.82 | HTR2A (0.70) | DRD2HTR2AKDM4EMAPTALOX15 | |
| Blonanserin SCHEMBL119669 | 0.82 | DRD2 (1.00) | DRD2HTR2AKDM4EMAPTALOX15 | |
| SCHEMBL7331193 | 0.82 | DRD2 (0.72) | DRD2HTR2AHRH3KDM4EMAPT | |
| Blonanserin SCHEMBL29379647 | 0.82 | DRD2 (1.00) | DRD2HTR2AKDM4EMAPTALOX15 | |
| SCHEMBL7334897 | 0.82 | DRD2 (1.00) | DRD2HTR2AKDM4EMAPTALOX15 | |
| SCHEMBL7328947 | 0.81 | HTR2A (0.71) | DRD2HTR2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385237-B1 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5021421-A | Psychotropic agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |