Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844174 | 0.79 | CHRNA7 (0.48) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL3840236 | 0.79 | CHRNA7 (0.48) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL1018551 | 0.78 | CHRNA7 (0.44) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL3204899 | 0.78 | CHRNA7 (0.53) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL4199213 | 0.77 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL5393414 | 0.76 | CHRNA7 (0.49) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL1542353 | 0.76 | CHRM1 (0.49) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL13444720 | 0.76 | CHRNA7 (0.57) | CHRM2CHRM1CHRNA7 | |
| SCHEMBL5343134 | 0.76 | CHRM2 (0.45) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL31304429 | 0.76 | CHRM2 (0.45) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921860-A | Quinuclidyl- and tropanyl-pyridyl ethers as 5-HT3 receptor antagonists | JOHN WYETH AND BROTHER, LIMITED (GB) | 1990-05-01 | — | — | US | disclosed |