SCHEMBL7325616

SCHEMBL7325616

CC(C)C(O)CC(O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)C(Cc1ccccc1)CS(=O)(=O)C(C)(C)C

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7312483 0.92 REN (0.65) REN
SCHEMBL7318241 0.92 REN (0.65) REN
SCHEMBL9287920 0.92 REN (0.69) REN
SCHEMBL7281295 0.92 REN (0.69) REN
SCHEMBL7299504 0.91 REN (0.62) REN
SCHEMBL9698134 0.91 REN (0.63) REN
Hydrochloric Acid SCHEMBL7302345 0.90 REN (0.61) REN
SCHEMBL6696481 0.90 REN (0.67) REN
SCHEMBL9699389 0.90 REN (0.62) REN
SCHEMBL7299894 0.90 REN (0.61) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0396065-A1 Novel amino acid derivatives possessing renin-inhibitory activities Japan Tobacco Inc. (JP) 1990-11-07 EP claimed
EP-0396065-A1 Novel amino acid derivatives possessing renin-inhibitory activities Japan Tobacco Inc. (JP) 1990-11-07 EP disclosed