SCHEMBL7325757

SCHEMBL7325757

CCCCc1nc(Cl)c(C(NC=O)OC)n1Cc1ccc(C(=O)c2ccccc2C(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 4/20 0.51
AGTR2 P50052 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393 0.84 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL7355519 0.81 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL394 0.79 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL640 0.78 AGTR1 (0.77) AGTR1AGTR2
SCHEMBL9275247 0.78 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL673 0.77 TLR7 (0.47)
SCHEMBL396 0.76 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL775 0.74 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL753 0.74 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL8791201 0.74 AGTR1 (0.64) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253310-A2 Angiotensin II receptor blocking imidazoles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-20 EP disclosed