Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316455 | 0.89 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9844155 | 0.89 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL9843837 | 0.89 | AGTR1 (0.59) | AGTR1PPARG | |
| SCHEMBL9844027 | 0.87 | AGTR1 (0.58) | AGTR1PPARG | |
| SCHEMBL7311106 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9843911 | 0.87 | AGTR1 (0.58) | AGTR1PPARG | |
| SCHEMBL9843777 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9843790 | 0.86 | PPARG (0.56) | AGTR1PPARG | |
| SCHEMBL7819440 | 0.85 | PPARG (0.61) | AGTR1PPARG | |
| SCHEMBL9231293 | 0.85 | PPARG (0.63) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071913-A | 2-(1H-TETRAZOL-5-YL)-4'-(AS-TRIAZIN-YLMETHYL)BIPHENYLS; CARDIOVASCULAR DISEASES, ESPECIALLY HYPERTENSION AND CONGESTIVE HEART FAILURE | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2000-06-06 | — | — | US | disclosed |