Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634765 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL1635627 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL1634763 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL2014327 | 0.77 | PSEN1 (0.38) | ALDH1A1HSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL1634121 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTPSEN1PSEN2APH1B | |
| SCHEMBL7324781 | 0.75 | SMN1; SMN2 (0.31) | GAACYP2C9 | |
| SCHEMBL21727232 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL16369922 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCYP2C9POLB | |
| SCHEMBL21707998 | 0.72 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL16030873 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MAPTKDM4EPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384380-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | disclosed |