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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7326019

CCOC(=O)CCN1CC(=O)N(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc(C(=N)N)cc3)cc2C1=O.O=C(O)C(F)(F)F

nearest known ligand 0.45

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ITGB3 P05106 19/20 0.45
▸ ITGA2B P08514 19/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7325545 0.92 ITGB3 (0.55) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL8836602 0.89 ITGB3 (0.52) ITGB3ITGA2B
SCHEMBL7325550 0.89 ITGB3 (0.46) ITGB3ITGA2B
SCHEMBL7363175 0.87 ITGB3 (0.59) ITGB3ITGA2B
SCHEMBL7333070 0.87 ITGB3 (0.51) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7322389 0.85 ITGB3 (0.57) ITGB3ITGA2B
SCHEMBL8837035 0.84 ITGB3 (0.48) ITGB3ITGA2B
SCHEMBL7323443 0.84 ITGB3 (0.55) ITGB3ITGA2B
SCHEMBL7323731 0.83 MAOB (0.38) —
SCHEMBL7363482 0.83 ITGB3 (0.59) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5674863-A BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR GENENTECH, INC. (US) 1997-10-07 — — US disclosed
US-5674865-A BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR GENENTECH, INC. (US) 1997-10-07 — — US disclosed
US-5663166-A ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING GENENTECH, INC. (US) 1997-09-02 — — US disclosed
US-5565449-A PLATELET AGGREGATION INHIBITORS GENENTECH, INC. (US) 1996-10-15 — — US disclosed
EP-0610334-B1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR GENENTECH INC (US) 1996-01-24 — — EP disclosed
EP-0610334-A1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. GENENTECH INC (US) 1994-08-17 — — EP disclosed
WO-1993008174-A1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR GENENTECH, INC. (US) 1993-04-29 — — WO disclosed