Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264 | 0.85 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL7313833 | 0.80 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL6971889 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL7315630 | 0.79 | AGTR1 (0.47) | AGTR1AGTR2TLR7 | |
| SCHEMBL9590556 | 0.79 | AGTR1 (0.79) | AGTR1AGTR2 | |
| SCHEMBL161 | 0.76 | AGTR1 (0.53) | AGTR1AGTR2TLR7 | |
| SCHEMBL11092792 | 0.75 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL320 | 0.75 | AGTR1 (0.52) | AGTR1AGTR2TLR7 | |
| SCHEMBL9530525 | 0.75 | AGTR1 (0.46) | AGTR1AGTR2TLR7 | |
| SCHEMBL7314663 | 0.75 | AGTR1 (0.48) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |