Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333667 | 0.88 | CYP1A2 (0.45) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL14666805 | 0.83 | CYP1A2 (0.43) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL17036700 | 0.80 | CYP1A2 (0.47) | CYP1A2ALOX5NR1I2PGRADORA3 | |
| SCHEMBL19085521 | 0.80 | TSHR (0.56) | MAPTKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL31325279 | 0.79 | CYP1A2 (0.59) | CYP1A2ALOX5NR1I2PGRADORA3 | |
| SCHEMBL31357582 | 0.79 | CYP1A2 (0.59) | CYP1A2ALOX5NR1I2PGRADORA3 | |
| SCHEMBL29740738 | 0.79 | CYP1A2 (0.59) | CYP1A2ALOX5NR1I2PGRADORA3 | |
| SCHEMBL2077620 | 0.79 | MAPT (0.56) | CYP1A2MAPTKMT2AALDH1A1TSHR | |
| SCHEMBL9716732 | 0.78 | CYP1A2 (0.48) | CYP1A2ALOX5NR1I2PGRADORA3 | |
| SCHEMBL4618714 | 0.78 | CYP1A2 (0.57) | CYP1A2ALOX5NR1I2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102890-A | Anxiolytic agents | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |