Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740738 | 0.85 | CYP1A2 (0.59) | CYP1A2ALOX5DNM1ALDH1A1TRPA1 | |
| SCHEMBL10851453 | 0.81 | APOBEC3A (0.56) | CYP1A2ALOX5DNM1ALDH1A1TRPA1 | |
| SCHEMBL22278960 | 0.79 | CYP1A2 (0.53) | CYP1A2ALOX5DNM1ALDH1A1TRPA1 | |
| SCHEMBL28713703 | 0.79 | CYP1A2 (0.53) | CYP1A2ALOX5DNM1ALDH1A1TRPA1 | |
| SCHEMBL6955669 | 0.79 | CYP1A2 (0.53) | CYP1A2ALOX5DNM1ALDH1A1TRPA1 | |
| SCHEMBL4618714 | 0.79 | CYP1A2 (0.57) | CYP1A2ALOX5DNM1ALDH1A1TRPA1 | |
| SCHEMBL127142 | 0.79 | CYP1A2 (0.57) | CYP1A2ALDH1A1TRPA1NR1I2PGR | |
| SCHEMBL10257417 | 0.78 | CA12 (0.41) | CYP1A2ALDH1A1TRPA1APOBEC3AAPOBEC3G | |
| SCHEMBL7326160 | 0.78 | CYP1A2 (0.52) | CYP1A2ALOX5DNM1ALDH1A1TRPA1 | |
| SCHEMBL14577186 | 0.77 | CA12 (0.50) | CYP1A2ALDH1A1TRPA1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |