Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323151 | 0.90 | REN (0.42) | REN | |
| SCHEMBL7316295 | 0.90 | REN (0.47) | REN | |
| SCHEMBL7316224 | 0.90 | REN (0.40) | REN | |
| Hydrochloric Acid SCHEMBL7355582 | 0.89 | REN (0.40) | REN | |
| SCHEMBL7322478 | 0.89 | REN (0.36) | REN | |
| SCHEMBL7322468 | 0.89 | REN (0.36) | REN | |
| SCHEMBL7326621 | 0.88 | REN (0.42) | RENPSMB5KMT2ACDYL2CDYL | |
| SCHEMBL7317681 | 0.88 | REN (0.42) | REN | |
| SCHEMBL7316055 | 0.88 | REN (0.42) | REN | |
| Hydrochloric Acid SCHEMBL7323642 | 0.87 | REN (0.42) | RENPSMB5KMT2ACDYL2CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231919-B1 | N-HETEROCYCLIC ALCOHOL RENIN INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1993-01-20 | — | — | EP | claimed |
| EP-0231919-B1 | N-HETEROCYCLIC ALCOHOL RENIN INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1993-01-20 | — | — | EP | disclosed |