Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7325747 | 0.94 | ITGB3 (0.68) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| Trifluoroacetic Acid SCHEMBL8959450 | 0.87 | ITGB3 (0.66) | ITGB3ITGA2BFFAR1 | |
| SCHEMBL8837187 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL7325755 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BFFAR1HDAC1HDAC6 | |
| SCHEMBL7359324 | 0.84 | ITGB3 (0.84) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| Trifluoroacetic Acid SCHEMBL7324537 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BFFAR1HDAC1 | |
| Trifluoroacetic Acid SCHEMBL7320877 | 0.81 | ITGB3 (0.90) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| Trifluoroacetic Acid SCHEMBL8959447 | 0.81 | ITGB3 (0.66) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| Trifluoroacetic Acid SCHEMBL7322477 | 0.80 | ITGB3 (0.61) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| Ethyl Acetate SCHEMBL7330809 | 0.79 | ITGB3 (0.85) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008174-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1993-04-29 | — | — | WO | disclosed |