SCHEMBL732667

SCHEMBL732667

CCCOc1ccc(N)cc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.58
ALDH1A1 P00352 4/20 0.58
GAA P10253 4/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 3/20 0.58
USP2 O75604 2/20 0.58
POLB P06746 2/20 0.58
CASP1 P29466 2/20 0.58
CASP7 P55210 2/20 0.58
TP53 P04637 1/20 0.58
HTT P42858 1/20 0.58
ATM Q13315 1/20 0.58
PTPN11 Q06124 5/20 0.51
S1PR3 Q99500 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
SCN1A P35498 1/20 0.51
SCN2A Q99250 1/20 0.51
SCN3A Q9NY46 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9363457 0.92 PTPN11 (0.57) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL730027 0.87 ALDH1A1 (0.63) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL16430427 0.87 MAPT (0.58) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL727942 0.87 HSD17B10 (0.56) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL28092143 0.84 MAPT (0.55) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL10349552 0.83 KDM4E (0.50) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL7371844 0.82 PTGDR2 (0.56) KDM4EPOLBPTPN11S1PR3PTPN1
SCHEMBL11078865 0.82 PTPN11 (0.52) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL11322929 0.82 KMT2A (0.55) ALDH1A1KMT2AKDM4EPOLBHTT
Hydrochloric Acid SCHEMBL7568583 0.82 GAA (0.56) MAPTALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003016615-A1 SINGLE BATH PROCESS FOR BLEACHING AND DYEING TEXTILES NOVOZYMES NORTH AMERICA, INC. (US) 2003-02-27 WO claimed
EP-0345728-B1 Dye composition for keratinous fiber KAO CORP (JP) 1994-09-14 EP claimed
EP-2708223-B1 DYEING AGENT AND USE FOR SAME AMANO ENZYME INC (JP) 2017-02-01 EP disclosed
US-8740994-B2 Dyeing agent and use for same AMANO ENZYME INC. (JP) 2014-06-03 US disclosed
EP-2708223-A1 DYEING AGENT AND USE FOR SAME Amano Enzyme Inc. (JP) 2014-03-19 EP disclosed
US-20140068875-A1 DYEING AGENT AND USE FOR SAME AMANO ENZYME INC (JP) 2014-03-13 US disclosed
US-8138357-B2 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field GIULIANI INTERNATIONAL LIMITED (IE) 2012-03-20 US disclosed
EP-1303631-B9 BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES DRITTE PATENTPORTFOLIO BETEILI (DE) 2010-09-08 EP disclosed
EP-1303631-B1 BIOTRANSFORMATION OF BIOLOGICALLY ACTIVE COMPOUNDS MADE OF VARIOUS CLASSES OF CHEMICAL SUBSTANCES BY MEANS OF LACCASE AND MANGANESE PEROXIDASE ENZYMES DRITTE PATENTPORTFOLIO BETEILI (DE) 2010-05-26 EP disclosed
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field GIULIANI INTERNATIONAL LIMITED (IE) 2009-05-07 US disclosed
US-6805718-B2 USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME NOVOZYMES A/S (DK) 2004-10-19 US disclosed
US-20010037532-A1 Enzymatic method for textile dyeing NOVOZYMES A/S (DK) 2001-11-08 US disclosed
US-6296672-B1 PEROXIDASE, OXIDOREDUCTASE, LACCASE NOVOZYMES A/S PATENTS (DK) 2001-10-02 US disclosed
WO-2001044563-A1 ENZYMATIC METHOD FOR TEXTILE DYEING NOVOZYMES NORTH AMERICA, INC. (US) 2001-06-21 WO disclosed
US-6036729-A DYEING, SOAKING MATERIAL WITH NAPHTHOLS, HYDROGEN PEROXIDE AND ENZYMES OF PEROXIDASE OR OXIDASE NOVO NORDISK A/S (DK) 2000-03-14 US disclosed
US-5972042-A DYEING SYSTEM WHICH COMPRISES ONE OR MORE MONO-, DI- OR POLYCYCLIC AROMATIC OR HETEROAROMATIC COMPOUNDS, AND HYDROGEN PEROXIDE SOURCE AND ENZYME EXHIBITING PEROXIDASE ACTIVITY OR ENZYME EXHIBITING OXIDASE ACTIVITY NOVO NORDISK A/S (DE) 1999-10-26 US disclosed
US-5925148-A TREATING IN AQUEOUS DYE LIQUOR WITH SYSTEM COMPRISING SUBSTITUTED AROMATIC COMPOUND, HYDROGEN PEROXIDE SOURCE AND PEROXIDASE ENZYME AND/OR OXIDASE ENZYME NOVO NORDISK A/S (DK) 1999-07-20 US disclosed
EP-0870082-A1 ENZYMATIC METHOD FOR DYEING NOVO NORDISK BIOCHEM NORTH AMERICA (US) 1998-10-14 EP disclosed
WO-1997023684-A1 ENZYMATIC METHOD FOR DYEING NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1997-07-03 WO disclosed
EP-0442204-A2 Pyrimidopyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1991-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field EGFR, ERBB3, FGFR3 MAPT 4833/4885ALDH1A1 2287/4885GAA 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.