Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320792 | 1.00 | KDM4E (0.56) | KDM4EPOLBL3MBTL1THRBATM | |
| SCHEMBL7327410 | 1.00 | KDM4E (0.56) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL7331359 | 0.98 | KDM4E (0.55) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL7333958 | 0.98 | KDM4E (0.55) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL3742446 | 0.98 | KDM4E (0.55) | KDM4EPOLBL3MBTL1THRBATM | |
| SCHEMBL7324398 | 0.98 | KDM4E (0.54) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL4274616 | 0.96 | KDM4E (0.52) | KDM4EPOLBL3MBTL1THRBATM | |
| SCHEMBL11119817 | 0.94 | KDM4E (0.50) | KDM4EPOLBL3MBTL1THRBATM | |
| Methylene Chloride SCHEMBL8889979 | 0.93 | KDM4E (0.51) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL11119814 | 0.93 | KDM4E (0.49) | KDM4EPOLBL3MBTL1THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221665-A | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0369391-A2 | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0057998-B1 | ALICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-08-08 | — | — | EP | disclosed |
| EP-0057998-A1 | Alicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |