Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327410 | 0.93 | KDM4E (0.56) | KDM4EPOLBL3MBTL1THRBATM | |
| SCHEMBL1320792 | 0.93 | KDM4E (0.56) | KDM4EPOLBL3MBTL1THRBATM | |
| SCHEMBL7326792 | 0.93 | KDM4E (0.56) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL3742446 | 0.92 | KDM4E (0.55) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL7333958 | 0.92 | KDM4E (0.55) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL7331359 | 0.92 | KDM4E (0.55) | KDM4EPOLBL3MBTL1THRBATM | |
| SCHEMBL7324398 | 0.92 | KDM4E (0.54) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL4274616 | 0.90 | KDM4E (0.52) | KDM4EPOLBL3MBTL1THRBATM | |
| SCHEMBL11119817 | 0.88 | KDM4E (0.50) | KDM4EPOLBL3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL11119814 | 0.86 | KDM4E (0.49) | KDM4EPOLBL3MBTL1THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641772-A | Condensed diazepinones, processes for preparing them and agents containing these compounds for treating diseases of the central nervous system and for promoting cerebral blood circulation | DR. KARL THOMAE GMBH (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5610155-A | ALZHEIMER'S | DR. KARL THOMAE GMBH (DE) | 1997-03-11 | — | — | US | disclosed |